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What is Sanguinol®?

  • Sanguinol® is derived from natural plant–Macleaya cordata. with a standardized amount of sanguinarine and chelerythrine, which are natural benzophenanthridine alkaloids (QBAs).They are known to have antimicrobial, antiinflflammatory, and immune-modulatory effects. Sanguinarine has been incorporated into swine, bovine, and poultry diets to decrease amino acid degradation, increase feed intake, and promote growth. Improvements in protein retention by reducing the intestinal decarboxylation of aromatic amino acids through the inhibition of L-aminoacid decarboxylase (Drsata, J., J. 1996 ) and enhancement of feed intake by modulating effects on the Trpserotonin pathway have also been suggested as part of their a mode of action (Mellor, S. 2001. ).

  • Sanguinol®  can be effectively quality controlled through quantitative analysis and characteristic maps using high-performance liquid chromatography

  • Sanguinol® has extremely strong stability, high temperature resistance and has no loss during granulation, extrusion and expansion

Sanguinarine

Sanguinarine

chelerythrine

chelerythrine

How does Sanguinol® work?

Sanguinol® contains Isoquinoline Alkaloids which works as the main active ingredients, in which sanguinarine is most important element. Sanguinarine has strong anti-inflammatory activity and is a strong and effective nuclear factor-κB (NF-κB) inhibitor. It can reduce the expression of inflammatory cytokines caused by a variety of stresses, thereby reducing the level of inflammation in the body. Niu and other studies have shown that sanguinarine can inhibit the activation of the NF-κB signaling pathway in cells in the organism, reduce the production of inducible nitric oxide, and achieve anti-inflammatory effects.

Sanguinol mechanism

What are benefits of Sanguinol®?

  • Prevent pathogens

  • Anti-inflammatory effect and enhance gut health

  • No resistance issues and no withdrawal periods

  • Improve animal performances – low FCR, growth promotion and low mortality

  • Good stability

  • Replace Antibiotic Growth Promoters (AGPs) in feed

Replacement of antibiotics in feed

Sanguinol®‘s main active ingredients are Sanguinarine and chelerythrine. Due to its strong anti-inflammatory activity, it improves intestinal health by inhibiting inflammation outbreaks in animals, thereby improving animal growth performance through a perfect “anti-inflammatory, intestinal regulation, and growth promotion” replacement mechanism for antibiotics.

Protein efficiency improvement

Sanguinol® can inhibit the activity of amino acid decarboxylase and monoamine oxidase, reduce amino acid degradation in the intestine and improve the digestion and absorption of protein and other nutrients in feed by maintaining the integrity of the intestine through anti-inflammatory and intestinal regulation effects.

Efficient growth promotion

By reducing intestinal inflammation in animals through anti-inflammatory and intestinal regulation effects, Sanguinol® gradually reduces ineffective nutrient loss, promotes syntheses metabolism, maintains intestinal integrity, optimizes intestinal microbial population, improves nutrient utilization efficiency, and promotes nutrient deposition in muscle tissues.

Healthy breeding

Inflammation is the root of animal health management, and Sanguinol® reduces animal inflammation levels to prevent and treat animal diseases more widely, systematically, and efficiently.

Who we are ?

Rongda Group,founded in Sep. 2001.

As a national high-tech enterprise, We focus on the R&D, production  and marketing of intestinal microbial nutrition and animal health products.  Through the development model of “dual cores + ecological farming”,  we provide comprehensive solutions for the ecological breeding industry  chain so as to fulfill the vision of promoting animal health, safeguarding  healthy humans.

Clients